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Glutathione Ethyl Ester Supplementation during Pancreatic Islet Isolation Improves Viability and Transplant Outcomes in a Murine Marginal Islet Mass Model

BACKGROUND: The success of pancreatic islet transplantation still faces many challenges, mainly related to cell damage during islet isolation and early post-transplant. The increased generation of reactive oxygen species (ROS) during islet isolation and the consumption of antioxidant defenses appear...

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Detalles Bibliográficos
Autores principales: Raposo do Amaral, Alexandre S., Pawlick, Rena L., Rodrigues, Erika, Costal, Flavia, Pepper, Andrew, Ferreira Galvão, Flávio H., Correa-Giannella, Maria Lucia, Shapiro, A. M.James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570543/
https://www.ncbi.nlm.nih.gov/pubmed/23424628
http://dx.doi.org/10.1371/journal.pone.0055288