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Glutathione Ethyl Ester Supplementation during Pancreatic Islet Isolation Improves Viability and Transplant Outcomes in a Murine Marginal Islet Mass Model
BACKGROUND: The success of pancreatic islet transplantation still faces many challenges, mainly related to cell damage during islet isolation and early post-transplant. The increased generation of reactive oxygen species (ROS) during islet isolation and the consumption of antioxidant defenses appear...
Autores principales: | Raposo do Amaral, Alexandre S., Pawlick, Rena L., Rodrigues, Erika, Costal, Flavia, Pepper, Andrew, Ferreira Galvão, Flávio H., Correa-Giannella, Maria Lucia, Shapiro, A. M.James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570543/ https://www.ncbi.nlm.nih.gov/pubmed/23424628 http://dx.doi.org/10.1371/journal.pone.0055288 |
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