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Functional Network Endophenotypes Unravel the Effects of Apolipoprotein E Epsilon 4 in Middle-Aged Adults

Apolipoprotein E-ε4 (APOE-ε4) accentuates memory decline, structural volume loss and cerebral amyloid deposition in cognitively healthy adults. We investigated whether APOE-ε4 carriers will show disruptions in the intrinsic cognitive networks, including the default mode (DMN), executive control (ECN...

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Detalles Bibliográficos
Autores principales: Goveas, Joseph S., Xie, Chunming, Chen, Gang, Li, Wenjun, Ward, B. Douglas, Franczak, Malgorzata B., Jones, Jennifer L., Antuono, Piero G., Li, Shi-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570545/
https://www.ncbi.nlm.nih.gov/pubmed/23424640
http://dx.doi.org/10.1371/journal.pone.0055902