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Testosterone Increases Susceptibility to Amebic Liver Abscess in Mice and Mediates Inhibition of IFNγ Secretion in Natural Killer T Cells

Amebic liver abscess (ALA), a parasitic disease due to infection with the protozoan Entamoeba histolytica, occurs age and gender dependent with strong preferences for adult males. Using a mouse model for ALA with a similar male bias for the disease, we have investigated the role of female and male s...

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Detalles Bibliográficos
Autores principales: Lotter, Hannelore, Helk, Elena, Bernin, Hannah, Jacobs, Thomas, Prehn, Cornelia, Adamski, Jerzy, González-Roldán, Nestor, Holst, Otto, Tannich, Egbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570563/
https://www.ncbi.nlm.nih.gov/pubmed/23424637
http://dx.doi.org/10.1371/journal.pone.0055694