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Frequent DNA Hypermethylation at the RASSF1A and APC Gene Loci in Prostate Cancer Patients of Pakistani Origin

DNA methylation has emerged as a potentially robust biomarker for prostate cancer (PCa). Since DNA methylomes appear to be disease as well as population specific, we have assessed the DNA methylation status of RASSF1A, APC, and p16 (potential biomarkers of PCa) in Pakistani population. Primary prost...

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Detalles Bibliográficos
Autores principales: Yaqinuddin, Ahmed, Qureshi, Sohail A., Pervez, Shahid, Bashir, Mohammed Umair, Nazir, Ressam, Abbas, Farhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570919/
https://www.ncbi.nlm.nih.gov/pubmed/23431474
http://dx.doi.org/10.1155/2013/627249