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High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring

Maternal exposures to environmental factors during pregnancy influence the risk of many chronic adult-onset diseases in the offspring. Here we investigate whether feeding pregnant rats a high-fat (HF)- or ethinyl-oestradiol (EE2)-supplemented diet affects carcinogen-induced mammary cancer risk in da...

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Detalles Bibliográficos
Autores principales: de Assis, Sonia, Warri, Anni, Cruz, M. Idalia, Laja, Olusola, Tian, Ye, Zhang, Bai, Wang, Yue, Huang, Tim Hui-Ming, Hilakivi-Clarke, Leena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570979/
https://www.ncbi.nlm.nih.gov/pubmed/22968699
http://dx.doi.org/10.1038/ncomms2058