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The TP53 fertility network

The TP53 gene, first described in 1979, was identified as a tumor suppressor gene in 1989, when it became clear that its product, the p53 nuclear phosphoprotein, was frequently inactivated in many different forms of cancers. Nicknamed “guardian of the genome”, TP53 occupies a central node in stress...

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Detalles Bibliográficos
Autores principales: Paskulin, Diego d’Avila, Paixão-Côrtes, Vanessa Rodrigues, Hainaut, Pierre, Bortolini, Maria Cátira, Ashton-Prolla, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571437/
https://www.ncbi.nlm.nih.gov/pubmed/23412905