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Identification of low molecular weight nuclear complexes containing integrase during the early stages of HIV-1 infection
BACKGROUND: HIV-1 replication requires integration of its reverse transcribed viral cDNA into a host cell chromosome. The DNA cutting and joining reactions associated to this key step are catalyzed by the viral protein integrase (IN). In infected cells, IN binds the viral cDNA, together with viral a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571920/ https://www.ncbi.nlm.nih.gov/pubmed/23369367 http://dx.doi.org/10.1186/1742-4690-10-13 |