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Identification of low molecular weight nuclear complexes containing integrase during the early stages of HIV-1 infection

BACKGROUND: HIV-1 replication requires integration of its reverse transcribed viral cDNA into a host cell chromosome. The DNA cutting and joining reactions associated to this key step are catalyzed by the viral protein integrase (IN). In infected cells, IN binds the viral cDNA, together with viral a...

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Detalles Bibliográficos
Autores principales: Gérard, Annabelle, Soler, Nicolas, Ségéral, Emmanuel, Belshan, Michael, Emiliani, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571920/
https://www.ncbi.nlm.nih.gov/pubmed/23369367
http://dx.doi.org/10.1186/1742-4690-10-13

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