Mechanistic analysis of multi-omics datasets to generate kinetic parameters for constraint-based metabolic models

BACKGROUND: Constraint-based modeling uses mass balances, flux capacity, and reaction directionality constraints to predict fluxes through metabolism. Although transcriptional regulation and thermodynamic constraints have been integrated into constraint-based modeling, kinetic rate laws have not bee...

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Detalles Bibliográficos
Autores principales: Cotten, Cameron, Reed, Jennifer L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571921/
https://www.ncbi.nlm.nih.gov/pubmed/23360254
http://dx.doi.org/10.1186/1471-2105-14-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571921/
https://www.ncbi.nlm.nih.gov/pubmed/23360254
http://dx.doi.org/10.1186/1471-2105-14-32

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