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Mechanistic analysis of multi-omics datasets to generate kinetic parameters for constraint-based metabolic models
BACKGROUND: Constraint-based modeling uses mass balances, flux capacity, and reaction directionality constraints to predict fluxes through metabolism. Although transcriptional regulation and thermodynamic constraints have been integrated into constraint-based modeling, kinetic rate laws have not bee...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571921/ https://www.ncbi.nlm.nih.gov/pubmed/23360254 http://dx.doi.org/10.1186/1471-2105-14-32 |