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Expression of CXCL12 receptors in B cells from Mexican Mestizos patients with systemic lupus erythematosus

BACKGROUND: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by B-cell hyper-reactivity and the production of pathogenic anti-nuclear-directed auto-antibodies (Abs). B-cell ontogeny is partly dependent on the CXCL12/CXCR4 axis for which the contribution to SLE pathoge...

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Detalles Bibliográficos
Autores principales: Biajoux, Vincent, Bignon, Alexandre, Freitas, Christelle, Martinez, Valérie, Thelen, Marcus, Lima, Guadalupe, Jakez-Ocampo, Juan, Emilie, Dominique, Llorente, Luis, Balabanian, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571925/
https://www.ncbi.nlm.nih.gov/pubmed/23244336
http://dx.doi.org/10.1186/1479-5876-10-251