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HuR cytoplasmic expression is associated with increased cyclin A expression and poor outcome with upper urinary tract urothelial carcinoma

BACKGROUND: HuR is an RNA-binding protein that post-transcriptionally modulates the expressions of various target genes implicated in carcinogenesis, such as CCNA2 encoding cyclin A. No prior study attempted to evaluate the significance of HuR expression in a large cohort with upper urinary tract ur...

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Detalles Bibliográficos
Autores principales: Liang, Peir-In, Li, Wei-Ming, Wang, Yu-Hui, Wu, Ting-Feng, Wu, Wen-Ren, Liao, Alex C, Shen, Kun-Hung, Wei, Yu-Ching, Hsing, Chung-Hsi, Shiue, Yow-Ling, Huang, Hsuan-Ying, Hsu, Han-Ping, Chen, Li-Tzon, Lin, Ching-Yih, Tai, Chein, Lin, Chun-Mao, Li, Chien-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571926/
https://www.ncbi.nlm.nih.gov/pubmed/23259573
http://dx.doi.org/10.1186/1471-2407-12-611