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High efficacy of CpG-ODN, Cetuximab and Cisplatin combination for very advanced ovarian xenograft tumors

BACKGROUND: To mimic clinical treatment situations in advanced human ovarian disease, we tested the efficacy of CpG-oligodeoxynucleotides (CpG-ODN), synthetic DNA sequences recognized by Toll-like receptor 9 and able to induce innate/adaptive immune responses, in combination with other possible ther...

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Detalles Bibliográficos
Autores principales: Sommariva, Michele, de Cesare, Michelandrea, Meini, Alessandra, Cataldo, Alessandra, Zaffaroni, Nadia, Tagliabue, Elda, Balsari, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571944/
https://www.ncbi.nlm.nih.gov/pubmed/23360557
http://dx.doi.org/10.1186/1479-5876-11-25