In Vivo Messenger RNA Introduction into the Central Nervous System Using Polyplex Nanomicelle

Messenger RNA (mRNA) introduction is a promising approach to produce therapeutic proteins and peptides without any risk of insertion mutagenesis into the host genome. However, it is difficult to introduce mRNA in vivo mainly because of the instability of mRNA under physiological conditions and its s...

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Detalles Bibliográficos
Autores principales: Uchida, Satoshi, Itaka, Keiji, Uchida, Hirokuni, Hayakawa, Kentaro, Ogata, Toru, Ishii, Takehiko, Fukushima, Shigeto, Osada, Kensuke, Kataoka, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571986/
https://www.ncbi.nlm.nih.gov/pubmed/23418537
http://dx.doi.org/10.1371/journal.pone.0056220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571986/
https://www.ncbi.nlm.nih.gov/pubmed/23418537
http://dx.doi.org/10.1371/journal.pone.0056220

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