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In Vivo Messenger RNA Introduction into the Central Nervous System Using Polyplex Nanomicelle
Messenger RNA (mRNA) introduction is a promising approach to produce therapeutic proteins and peptides without any risk of insertion mutagenesis into the host genome. However, it is difficult to introduce mRNA in vivo mainly because of the instability of mRNA under physiological conditions and its s...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571986/ https://www.ncbi.nlm.nih.gov/pubmed/23418537 http://dx.doi.org/10.1371/journal.pone.0056220 |