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Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres

Growing evidence suggests that the cancer stem cell phenotype in melanoma is dynamically regulated. Therefore, effective therapies have to target simultaneously bulk tumor cells and melanoma stem-like cells. The aim of the present study was to investigate the effects of parthenolide on heterogeneous...

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Detalles Bibliográficos
Autores principales: Czyz, Malgorzata, Koprowska, Kamila, Sztiller-Sikorska, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571995/
https://www.ncbi.nlm.nih.gov/pubmed/23192276
http://dx.doi.org/10.4161/cbt.22952