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A molecular case report: Functional assay of tyrosine kinase inhibitors in cells from a patient’s primary renal cell carcinoma
Current therapies for Renal Cell Carcinoma favor vascular endothelial growth factor receptor (VEGF-R) tyrosine kinase (TK) inhibitors (TKIs). In theory, these are most applicable in tumors that have lost VHL-with subsequent stabilization of HIF and upregulation of VEGF. A subset of patients harbor p...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572006/ https://www.ncbi.nlm.nih.gov/pubmed/23192268 http://dx.doi.org/10.4161/cbt.22960 |