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MicroRNAs Distinguish Cytogenetic Subgroups in Pediatric AML and Contribute to Complex Regulatory Networks in AML-Relevant Pathways

BACKGROUND: The role of microRNAs (miRNAs), important post-transcriptional regulators, in the pathogenesis of acute myeloid leukemia (AML) is just emerging and has been mainly studied in adults. First studies in children investigate single selected miRNAs, however, a comprehensive overview of miRNA...

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Detalles Bibliográficos
Autores principales: Daschkey, Svenja, Röttgers, Silja, Giri, Anamika, Bradtke, Jutta, Teigler-Schlegel, Andrea, Meister, Gunter, Borkhardt, Arndt, Landgraf, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572007/
https://www.ncbi.nlm.nih.gov/pubmed/23418555
http://dx.doi.org/10.1371/journal.pone.0056334