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Activity of the Heat Shock Protein 90 Inhibitor Ganetespib in Melanoma
Heat shock protein 90 (HSP90) is involved in the regulation of diverse biological processes such as cell signaling, proliferation and survival, and has been recently recognized as a potential target for cancer therapy. Ganetespib is a potent ATP competitive inhibitor of HSP90. Ganetespib downregulat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572008/ https://www.ncbi.nlm.nih.gov/pubmed/23418523 http://dx.doi.org/10.1371/journal.pone.0056134 |