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Activity of the Heat Shock Protein 90 Inhibitor Ganetespib in Melanoma

Heat shock protein 90 (HSP90) is involved in the regulation of diverse biological processes such as cell signaling, proliferation and survival, and has been recently recognized as a potential target for cancer therapy. Ganetespib is a potent ATP competitive inhibitor of HSP90. Ganetespib downregulat...

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Detalles Bibliográficos
Autores principales:	Wu, Xinqi, Marmarelis, Melina E., Hodi, F. Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572008/ https://www.ncbi.nlm.nih.gov/pubmed/23418523 http://dx.doi.org/10.1371/journal.pone.0056134

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