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Proliferation-Linked Apoptosis of Adoptively Transferred T Cells after IL-15 Administration in Macaques
The adoptive transfer of antigen-specific effector T cells is being used to treat human infections and malignancy. T cell persistence is a prerequisite for therapeutic efficacy, but reliably establishing a high-level and durable T cell response by transferring cultured CD8(+) T cells remains challen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572023/ https://www.ncbi.nlm.nih.gov/pubmed/23418547 http://dx.doi.org/10.1371/journal.pone.0056268 |