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Characterization of the Gbx1(−/−) Mouse Mutant: A Requirement for Gbx1 in Normal Locomotion and Sensorimotor Circuit Development

The Gbx class of homeobox genes encodes DNA binding transcription factors involved in regulation of embryonic central nervous system (CNS) development. Gbx1 is dynamically expressed within spinal neuron progenitor pools and becomes restricted to the dorsal mantle zone by embryonic day (E) 12.5. Here...

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Detalles Bibliográficos
Autores principales: Buckley, Desirè M., Burroughs-Garcia, Jessica, Lewandoski, Mark, Waters, Samuel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572027/
https://www.ncbi.nlm.nih.gov/pubmed/23418536
http://dx.doi.org/10.1371/journal.pone.0056214