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Characterization of the Gbx1(−/−) Mouse Mutant: A Requirement for Gbx1 in Normal Locomotion and Sensorimotor Circuit Development
The Gbx class of homeobox genes encodes DNA binding transcription factors involved in regulation of embryonic central nervous system (CNS) development. Gbx1 is dynamically expressed within spinal neuron progenitor pools and becomes restricted to the dorsal mantle zone by embryonic day (E) 12.5. Here...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572027/ https://www.ncbi.nlm.nih.gov/pubmed/23418536 http://dx.doi.org/10.1371/journal.pone.0056214 |