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Unraveling Complex Interplay between Heat Shock Factor 1 and 2 Splicing Isoforms
Chaperone synthesis in response to proteotoxic stress is dependent on a family of transcription factors named heat shock factors (HSFs). The two main factors in this family, HSF1 and HSF2, are co-expressed in numerous tissues where they can interact and form heterotrimers in response to proteasome i...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572029/ https://www.ncbi.nlm.nih.gov/pubmed/23418516 http://dx.doi.org/10.1371/journal.pone.0056085 |