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Unraveling Complex Interplay between Heat Shock Factor 1 and 2 Splicing Isoforms

Chaperone synthesis in response to proteotoxic stress is dependent on a family of transcription factors named heat shock factors (HSFs). The two main factors in this family, HSF1 and HSF2, are co-expressed in numerous tissues where they can interact and form heterotrimers in response to proteasome i...

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Detalles Bibliográficos
Autores principales: Lecomte, Sylvain, Reverdy, Léa, Le Quément, Catherine, Le Masson, Florent, Amon, Axelle, Le Goff, Pascale, Michel, Denis, Christians, Elisabeth, Le Dréan, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572029/
https://www.ncbi.nlm.nih.gov/pubmed/23418516
http://dx.doi.org/10.1371/journal.pone.0056085