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[(18)F]DPA-714: Direct Comparison with [(11)C]PK11195 in a Model of Cerebral Ischemia in Rats

PURPOSE: Neuroinflammation is involved in several brain disorders and can be monitored through expression of the translocator protein 18 kDa (TSPO) on activated microglia. In recent years, several new PET radioligands for TSPO have been evaluated in disease models. [(18)F]DPA-714 is a TSPO radiotrac...

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Detalles Bibliográficos
Autores principales: Boutin, Hervé, Prenant, Christian, Maroy, Renaud, Galea, James, Greenhalgh, Andrew D., Smigova, Alison, Cawthorne, Christopher, Julyan, Peter, Wilkinson, Shane M., Banister, Samuel D., Brown, Gavin, Herholz, Karl, Kassiou, Michael, Rothwell, Nancy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572061/
https://www.ncbi.nlm.nih.gov/pubmed/23418569
http://dx.doi.org/10.1371/journal.pone.0056441