The Nonconventional MHC Class II Molecule DM Governs Diabetes Susceptibility in NOD Mice

The spontaneous destruction of insulin producing pancreatic beta cells in non-obese diabetic (NOD) mice provides a valuable model of type 1 diabetes. As in humans, disease susceptibility is controlled by the classical MHC class II genes that guide CD4(+) T cell responses to self and foreign antigens...

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Detalles Bibliográficos
Autores principales: Morgan, Marc A. J., Muller, Pari S. S., Mould, Arne, Newland, Stephen A., Nichols, Jennifer, Robertson, Elizabeth J., Cooke, Anne, Bikoff, Elizabeth K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572069/
https://www.ncbi.nlm.nih.gov/pubmed/23418596
http://dx.doi.org/10.1371/journal.pone.0056738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572069/
https://www.ncbi.nlm.nih.gov/pubmed/23418596
http://dx.doi.org/10.1371/journal.pone.0056738

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