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Mammalian TIMELESS Is Involved in Period Determination and DNA Damage-Dependent Phase Advancing of the Circadian Clock
The transcription/translation feedback loop-based molecular oscillator underlying the generation of circadian gene expression is preserved in almost all organisms. Interestingly, the animal circadian clock proteins CRYPTOCHROME (CRY), PERIOD (PER) and TIMELESS (TIM) are strongly conserved at the ami...
Autores principales: | Engelen, Erik, Janssens, Roel C., Yagita, Kazuhiro, Smits, Veronique A. J., van der Horst, Gijsbertus T. J., Tamanini, Filippo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572085/ https://www.ncbi.nlm.nih.gov/pubmed/23418588 http://dx.doi.org/10.1371/journal.pone.0056623 |
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