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Proprotein Convertase Furin Regulates Apoptosis and Proliferation of Granulosa Cells in the Rat Ovary

Folliculogenesis is tightly controlled by a series of hormones, growth factors and cytokines, many of which are secreted as proproteins and require processing by proteases before becoming functional. Furin is a member of the subtilisin-like proteases that activate large numbers of proprotein substra...

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Detalles Bibliográficos
Autores principales: Yang, Xiaokui, Wang, Qingxin, Gao, Zhiying, Zhou, Zhi, Peng, Sha, Chang, Wen-Lin, Lin, Hai-Yan, Zhang, Weiyuan, Wang, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572104/
https://www.ncbi.nlm.nih.gov/pubmed/23418414
http://dx.doi.org/10.1371/journal.pone.0050479