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Functional-Network-Based Gene Set Analysis Using Gene-Ontology

To account for the functional non-equivalence among a set of genes within a biological pathway when performing gene set analysis, we introduce GOGANPA, a network-based gene set analysis method, which up-weights genes with functions relevant to the gene set of interest. The genes are weighted accordi...

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Detalles Bibliográficos
Autores principales: Chang, Billy, Kustra, Rafal, Tian, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572115/
https://www.ncbi.nlm.nih.gov/pubmed/23418449
http://dx.doi.org/10.1371/journal.pone.0055635