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Paraoxonase 1 Gene Polymorphism Does Not Affect Clopidogrel Response Variability but Is Associated with Clinical Outcome after PCI

BACKGROUND: Paraoxonase (PON) is a high-density-lipoprotein (HDL) associated enzyme with antioxidative and anti-atherogenic property. Its function is associated with coronary artery disease and its activity genetically controlled. We evaluated whether genetic variation of PON-1 is associated with cl...

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Detalles Bibliográficos
Autores principales: Park, Kyung Woo, Park, Jin Joo, Kang, Jeehoon, Jeon, Ki-Hyun, Kang, Si-Hyuck, Han, Jung-Kyu, Lee, Sang Eun, Yang, Han-Mo, Lee, Hae-Young, Kang, Hyun-Jae, Koo, Bon-Kwon, Oh, Byung-Hee, Park, Young-Bae, Kim, Hyo-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572125/
https://www.ncbi.nlm.nih.gov/pubmed/23418418
http://dx.doi.org/10.1371/journal.pone.0052779