Silencing of APE1 Enhances Sensitivity of Human Hepatocellular Carcinoma Cells to Radiotherapy In Vitro and in a Xenograft Model

Resistance to radiotherapy is a key limitation for the treatment of human hepatocellular carcinoma (HCC). To overcome this problem, we investigated the correlation between radioresistance and the human apurinic/apyrimidinic endonuclease (APE1), a bifunctional protein, which plays an important role i...

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Detalles Bibliográficos
Autores principales: Cun, Yanping, Dai, Nan, Xiong, Chengjie, Li, Mengxia, Sui, Jiangdong, Qian, Chengyuan, Li, Zheng, Wang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572126/
https://www.ncbi.nlm.nih.gov/pubmed/23418439
http://dx.doi.org/10.1371/journal.pone.0055313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572126/
https://www.ncbi.nlm.nih.gov/pubmed/23418439
http://dx.doi.org/10.1371/journal.pone.0055313

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