Cargando…

Silencing of APE1 Enhances Sensitivity of Human Hepatocellular Carcinoma Cells to Radiotherapy In Vitro and in a Xenograft Model

Resistance to radiotherapy is a key limitation for the treatment of human hepatocellular carcinoma (HCC). To overcome this problem, we investigated the correlation between radioresistance and the human apurinic/apyrimidinic endonuclease (APE1), a bifunctional protein, which plays an important role i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cun, Yanping, Dai, Nan, Xiong, Chengjie, Li, Mengxia, Sui, Jiangdong, Qian, Chengyuan, Li, Zheng, Wang, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572126/ https://www.ncbi.nlm.nih.gov/pubmed/23418439 http://dx.doi.org/10.1371/journal.pone.0055313

Ejemplares similares

Retraction: Silencing of APE1 Enhances Sensitivity of Human Hepatocellular Carcinoma Cells to Radiotherapy In Vitro and in a Xenograft Model
Publicado: (2023)

Identification of a novel potential antitumor activity of gossypol as an APE1/Ref-1 inhibitor
por: Qian, Chengyuan, et al.
Publicado: (2014)

Human Apurinic/Apyrimidinic Endonuclease siRNA Inhibits the Angiogenesis Induced by X-Ray Irradiation in Lung Cancer Cells
por: Gu, Xianqing, et al.
Publicado: (2013)

Distinct APE1 Activities Affect the Regulation of VEGF Transcription Under Hypoxic Conditions
por: Li, Mengxia, et al.
Publicado: (2019)

APE1 may influence CD4+ naïve T cells on recurrence free survival in early stage NSCLC
por: Li, Yanping, et al.
Publicado: (2021)

MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression
por: Liang, Wei, et al.
Publicado: (2019)

Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1
por: Sui, Jiangdong, et al.
Publicado: (2014)

GADD45α sensitizes cervical cancer cells to radiotherapy via increasing cytoplasmic APE1 level
por: Li, Qing, et al.
Publicado: (2018)

APE1 deficiency promotes cellular senescence and premature aging features
por: Li, Mengxia, et al.
Publicado: (2018)

APE1 stimulates EGFR-TKI resistance by activating Akt signaling through a redox-dependent mechanism in lung adenocarcinoma
por: Lu, Guo-Shou, et al.
Publicado: (2018)

From APE to APE-100: present and future of the APE project
por: Bacilieri, P, et al.
Publicado: (1988)

Context-sensitive adjustment of pointing in great apes
por: Tauzin, Tibor, et al.
Publicado: (2020)

Functional Assessment of Population and Tumor-Associated APE1 Protein Variants
por: Illuzzi, Jennifer L., et al.
Publicado: (2013)

Moscatilin Inhibits Growth of Human Esophageal Cancer Xenograft and Sensitizes Cancer Cells to Radiotherapy
por: Chen, Wun-Ke, et al.
Publicado: (2019)

Apes
por: Lowenstine, Linda J., et al.
Publicado: (2018)

Man-Apes or Ape-Men? The Story of Discoveries in Africa
por: Gardner, William U.
Publicado: (1967)

The regulatory role of APE1 in epithelial‐to‐mesenchymal transition and in determining EGFR‐TKI responsiveness in non‐small‐cell lung cancer
por: Yang, Xiao, et al.
Publicado: (2018)

Apurinic/apyrimidinic endonuclease 1 regulates angiogenesis in a transforming growth factor β-dependent manner in human osteosarcoma
por: Jiang, Xuan, et al.
Publicado: (2015)

The role of APE/Ref-1 signaling pathway in hepatocellular carcinoma progression
por: YANG, ZHEN, et al.
Publicado: (2014)

The mentality of apes
por: Köhler, Wolfgang, 1887-1967
Publicado: (1959)

The naked ape
por: Morris, Desmond
Publicado: (1967)

Men and apes
por: Morris, Ramona
Publicado: (1966)

The apes of God /
por: Lewis, Wyndham, 1882-1957

Monkeys and apes
por: Napier, P. H. (Prue H.)

The APE computer
por: Rapuano, F
Publicado: (1987)

The Ape's Tail
por: Cherian, Ajith
Publicado: (2019)

MicroRNA-765 Enhances the Anti-Angiogenic Effect of CDDP via APE1 in Osteosarcoma
por: Liang, Wei, et al.
Publicado: (2017)

Serum APE1 as a predictive marker for platinum-based chemotherapy of non-small cell lung cancer patients
por: Zhang, Shiheng, et al.
Publicado: (2016)

Inhibition of Cell Proliferation and Growth of Pancreatic Cancer by Silencing of Carbohydrate Sulfotransferase 15 In Vitro and in a Xenograft Model
por: Takakura, Kazuki, et al.
Publicado: (2015)

Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer
por: Ren, Tao, et al.
Publicado: (2015)

Computers go APE
Publicado: (1994)

The ape-man within
por: De Camp, L. Sprague (Lyon Sprague), 1907-2000
Publicado: (1995)

The love of monkeys and apes
por: Freeman, Dan
Publicado: (1977)

Apes giants and man
por: Weidenreich, Franz, 1873-
Publicado: (1946)

Apes, lice and prehistory
por: Weiss, Robin A
Publicado: (2009)

Moral ape philosophy
por: de Boer, Jelle
Publicado: (2011)

The APE100 project
por: Avico, N, et al.
Publicado: (1990)

Status of APE projects
por: Alfieri, R, et al.
Publicado: (2001)

Mivart on Man and Apes
Publicado: (1874)

The goal of ape pointing
por: Halina, Marta, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ctuatcgj22s1qjpcm02v45iobi