Novel Pancreatic Endocrine Maturation Pathways Identified by Genomic Profiling and Causal Reasoning

We have used a previously unavailable model of pancreatic development, derived in vitro from human embryonic stem cells, to capture a time-course of gene, miRNA and histone modification levels in pancreatic endocrine cells. We investigated whether it is possible to better understand, and hence contr...

Descripción completa

Detalles Bibliográficos
Autores principales: Gutteridge, Alex, Rukstalis, J. Michael, Ziemek, Daniel, Tié, Mark, Ji, Lin, Ramos-Zayas, Rebeca, Nardone, Nancy A., Norquay, Lisa D., Brenner, Martin B., Tang, Kim, McNeish, John D., Rowntree, Rebecca K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572136/
https://www.ncbi.nlm.nih.gov/pubmed/23418498
http://dx.doi.org/10.1371/journal.pone.0056024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572136/
https://www.ncbi.nlm.nih.gov/pubmed/23418498
http://dx.doi.org/10.1371/journal.pone.0056024

Ejemplares similares