Deregulated Nras Expression in Knock-In Animals Harboring a Gammaretroviral Long Terminal Repeat at the Nras/Csde1 Locus

To investigate mechanisms and phenotypic effects of insertional mutagenesis by gammaretroviruses, we have developed mouse lines containing a single Akv 1-99 long terminal repeat (LTR) and a floxed PGK/Tn5 neomycin cassette at the Nras proto-oncogene at positions previously identified as viral integr...

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Detalles Bibliográficos
Autores principales: Ballarín-González, Borja, Lassen, Louise Berkhoudt, Jessen, Randi, Füchtbauer, Annette, Füchtbauer, Ernst-Martin, Pedersen, Finn Skou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572152/
https://www.ncbi.nlm.nih.gov/pubmed/23418499
http://dx.doi.org/10.1371/journal.pone.0056029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572152/
https://www.ncbi.nlm.nih.gov/pubmed/23418499
http://dx.doi.org/10.1371/journal.pone.0056029

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