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Two Dynamin-2 Genes Are Required for Normal Zebrafish Development

Dynamin-2 (DNM2) is a large GTPase involved in clathrin-mediated endocytosis and related trafficking pathways. Mutations in human DNM2 cause two distinct neuromuscular disorders: centronuclear myopathy and Charcot-Marie-Tooth disease. Zebrafish have been shown to be an excellent animal model for man...

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Detalles Bibliográficos
Autores principales: Gibbs, Elizabeth M., Davidson, Ann E., Trickey-Glassman, Arden, Backus, Carey, Hong, Yu, Sakowski, Stacey A., Dowling, James J., Feldman, Eva L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572173/
https://www.ncbi.nlm.nih.gov/pubmed/23418470
http://dx.doi.org/10.1371/journal.pone.0055888