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Safety and Immunogenicity of DNA and MVA HIV-1 Subtype C Vaccine Prime-Boost Regimens: A Phase I Randomised Trial in HIV-Uninfected Indian Volunteers

STUDY DESIGN: A randomized, double-blind, placebo controlled phase I trial. METHODS: The trial was conducted in 32 HIV-uninfected healthy volunteers to assess the safety and immunogenicity of prime-boost vaccination regimens with either 2 doses of ADVAX, a DNA vaccine containing Chinese HIV-1 subtyp...

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Detalles Bibliográficos
Autores principales: Mehendale, Sanjay, Thakar, Madhuri, Sahay, Seema, Kumar, Makesh, Shete, Ashwini, Sathyamurthi, Pattabiraman, Verma, Amita, Kurle, Swarali, Shrotri, Aparna, Gilmour, Jill, Goyal, Rajat, Dally, Len, Sayeed, Eddy, Zachariah, Devika, Ackland, James, Kochhar, Sonali, Cox, Josephine H., Excler, Jean-Louis, Kumaraswami, Vasanthapuram, Paranjape, Ramesh, Ramanathan, Vadakkuppatu Devasenapathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572184/
https://www.ncbi.nlm.nih.gov/pubmed/23418465
http://dx.doi.org/10.1371/journal.pone.0055831