Pharmacokinetic and pharmacodynamic effects of comedication of clopidogrel and dabigatran etexilate in healthy male volunteers

PURPOSE: To evaluate the pharmacokinetic and pharmacodynamic effects of concomitant administration of single loading doses of clopidogrel or multiple doses of clopidogrel with multiple doses of dabigatran etexilate. METHODS: This was an open-label trial in healthy male subjects. In part 1 (pilot, n ...

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Detalles Bibliográficos
Autores principales: Härtter, Sebastian, Sennewald, Regina, Schepers, Cornelia, Baumann, Sybille, Fritsch, Holger, Friedman, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572379/
https://www.ncbi.nlm.nih.gov/pubmed/22782539
http://dx.doi.org/10.1007/s00228-012-1304-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572379/
https://www.ncbi.nlm.nih.gov/pubmed/22782539
http://dx.doi.org/10.1007/s00228-012-1304-8

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