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Association between DNA methylation of HSPB1 and death in low Gleason score prostate cancer

BACKGROUND: Heat shock protein 27 (Hsp-27) encoded by gene HSPB1 is a critical regulator of the behavioral phenotype of human prostate cancer (PCa) cells, enhanced expression being associated with highly aggressive disease and poor clinical outcome. In contrast, the protein is not expressed in PCas...

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Detalles Bibliográficos
Autores principales: Vasiljević, N, Ahmad, A S, Beesley, C, Thorat, M A, Fisher, G, Berney, D M, Møller, H, Yu, Y, Lu, Y-J, Cuzick, J, Foster, C S, Lorincz, A T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572391/
https://www.ncbi.nlm.nih.gov/pubmed/23165430
http://dx.doi.org/10.1038/pcan.2012.47