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Association between DNA methylation of HSPB1 and death in low Gleason score prostate cancer
BACKGROUND: Heat shock protein 27 (Hsp-27) encoded by gene HSPB1 is a critical regulator of the behavioral phenotype of human prostate cancer (PCa) cells, enhanced expression being associated with highly aggressive disease and poor clinical outcome. In contrast, the protein is not expressed in PCas...
Autores principales: | Vasiljević, N, Ahmad, A S, Beesley, C, Thorat, M A, Fisher, G, Berney, D M, Møller, H, Yu, Y, Lu, Y-J, Cuzick, J, Foster, C S, Lorincz, A T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572391/ https://www.ncbi.nlm.nih.gov/pubmed/23165430 http://dx.doi.org/10.1038/pcan.2012.47 |
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