Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans

Severe mitochondria deficiency leads to a number of devastating degenerative disorders, yet, mild mitochondrial dysfunction in different species, including the nematode Caenorhabditis elegans, can have pro-longevity effects. This apparent paradox indicates that cellular adaptation to partial mitocho...

Descripción completa

Detalles Bibliográficos
Autores principales: Schiavi, Alfonso, Torgovnick, Alessandro, Kell, Alison, Megalou, Evgenia, Castelein, Natascha, Guccini, Ilaria, Marzocchella, Laura, Gelino, Sara, Hansen, Malene, Malisan, Florence, Condò, Ivano, Bei, Roberto, Rea, Shane L., Braeckman, Bart P., Tavernarakis, Nektarios, Testi, Roberto, Ventura, Natascia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572394/
https://www.ncbi.nlm.nih.gov/pubmed/23247094
http://dx.doi.org/10.1016/j.exger.2012.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572394/
https://www.ncbi.nlm.nih.gov/pubmed/23247094
http://dx.doi.org/10.1016/j.exger.2012.12.002

Ejemplares similares