Pathogenic Mutation in VPS35 Impairs Its Protection against MPP(+) Cytotoxicity

Parkinson's disease primarily results from progressive degeneration of dopaminergic neurons in the substantia nigra. Both neuronal toxicants and genetic factors are suggested to be involved in the disease pathogenesis. The mitochondrial toxicant 1-methyl-4-phenylpyridinium (MPP(+)) shows a high...

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Detalles Bibliográficos
Autores principales: Bi, Fangfang, Li, Fang, Huang, Cao, Zhou, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572397/
https://www.ncbi.nlm.nih.gov/pubmed/23411763
http://dx.doi.org/10.7150/ijbs.5617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572397/
https://www.ncbi.nlm.nih.gov/pubmed/23411763
http://dx.doi.org/10.7150/ijbs.5617

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