Adaptive Bayesian Approach to Clinical Trial Renal Impairment Biomarker Signal from Urea and Creatinine

A major concern with the identification of renal toxicity using the traditional biomarkers, urea and creatinine, is that toxicity signal definitions are not sensitive to medically important changes in these biomarkers. Traditional renal signal definitions for urea and creatinine have not adequately...

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Detalles Bibliográficos
Autores principales: Sottas, Pierre-Edouard, Kapke, Gordon F., Leroux, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572398/
https://www.ncbi.nlm.nih.gov/pubmed/23411942
http://dx.doi.org/10.7150/ijbs.5225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572398/
https://www.ncbi.nlm.nih.gov/pubmed/23411942
http://dx.doi.org/10.7150/ijbs.5225

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