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HtrA3 Is Downregulated in Cancer Cell Lines and Significantly Reduced in Primary Serous and Granulosa Cell Ovarian Tumors

Objective. The high temperature requirement factor A3 (HtrA3) is a serine protease homologous to bacterial HtrA. Four human HtrAs have been identified. HtrA1 and HtrA3 share a high degree of domain organization and are downregulated in a number of cancers, suggesting a widespread loss of these prote...

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Detalles Bibliográficos
Autores principales: Singh, Harmeet, Li, Ying, Fuller, Peter J, Harrison, Craig, Rao, Jyothsna, Stephens, Andrew N, Nie, Guiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572407/
https://www.ncbi.nlm.nih.gov/pubmed/23412729
http://dx.doi.org/10.7150/jca.5702