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Mapping single molecule sequencing reads using basic local alignment with successive refinement (BLASR): application and theory

BACKGROUND: Recent methods have been developed to perform high-throughput sequencing of DNA by Single Molecule Sequencing (SMS). While Next-Generation sequencing methods may produce reads up to several hundred bases long, SMS sequencing produces reads up to tens of kilobases long. Existing alignment...

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Detalles Bibliográficos
Autores principales: Chaisson, Mark J, Tesler, Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572422/
https://www.ncbi.nlm.nih.gov/pubmed/22988817
http://dx.doi.org/10.1186/1471-2105-13-238