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Mapping single molecule sequencing reads using basic local alignment with successive refinement (BLASR): application and theory
BACKGROUND: Recent methods have been developed to perform high-throughput sequencing of DNA by Single Molecule Sequencing (SMS). While Next-Generation sequencing methods may produce reads up to several hundred bases long, SMS sequencing produces reads up to tens of kilobases long. Existing alignment...
Autores principales: | Chaisson, Mark J, Tesler, Glenn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572422/ https://www.ncbi.nlm.nih.gov/pubmed/22988817 http://dx.doi.org/10.1186/1471-2105-13-238 |
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