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Potent DNA damage by polyhalogenated quinones and H(2)O(2) via a metal-independent and Intercalation-enhanced oxidation mechanism

Polyhalogenated quinones are a class of carcinogenic intermediates. We found recently that the highly reactive and biologically/environmentally important ·OH can be produced by polyhalogenated quinones and H(2)O(2) independent of transition metal ions. However, it is not clear whether this unusual m...

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Detalles Bibliográficos
Autores principales: Yin, Ruichuan, Zhang, Dapeng, Song, Yuling, Zhu, Ben-Zhan, Wang, Hailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572447/
https://www.ncbi.nlm.nih.gov/pubmed/23429247
http://dx.doi.org/10.1038/srep01269