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Potent DNA damage by polyhalogenated quinones and H(2)O(2) via a metal-independent and Intercalation-enhanced oxidation mechanism
Polyhalogenated quinones are a class of carcinogenic intermediates. We found recently that the highly reactive and biologically/environmentally important ·OH can be produced by polyhalogenated quinones and H(2)O(2) independent of transition metal ions. However, it is not clear whether this unusual m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572447/ https://www.ncbi.nlm.nih.gov/pubmed/23429247 http://dx.doi.org/10.1038/srep01269 |