Human castration resistant prostate cancer rather prefer to decreased 5α-reductase activity

Physiologically relevant steroid 5α-reductase (SRD5A) activity that is essential for dihydrotestosterone (DHT) biosynthesis in human castration-resistant prostate cancer (CRPC) has not been fully characterized yet. In this study to ascertain the potential SRD5A activity, we cultured two human CRPC c...

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Detalles Bibliográficos
Autores principales: Kosaka, Takeo, Miyajima, Akira, Nagata, Hirohiko, Maeda, Takahiro, Kikuchi, Eiji, Oya, Mototsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572449/
https://www.ncbi.nlm.nih.gov/pubmed/23429215
http://dx.doi.org/10.1038/srep01268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572449/
https://www.ncbi.nlm.nih.gov/pubmed/23429215
http://dx.doi.org/10.1038/srep01268

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