Lysophosphatidic Acid Promotes Cell Migration through STIM1- and Orai1-Mediated Ca(2+)(i) Mobilization and NFAT2 Activation

Lysophosphatidic acid (LPA) enhances cell migration and promotes wound healing in vivo, but the intracellular signaling pathways regulating these processes remain incompletely understood. Here we investigated the involvement of agonist-induced Ca(2+) entry and STIM1 and Orai1 proteins in regulating...

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Detalles Bibliográficos
Autores principales: Jans, Ralph, Mottram, Laura, Johnson, Darren L, Brown, Anna M, Sikkink, Stephen, Ross, Kehinde, Reynolds, Nick J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572452/
https://www.ncbi.nlm.nih.gov/pubmed/23096711
http://dx.doi.org/10.1038/jid.2012.370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572452/
https://www.ncbi.nlm.nih.gov/pubmed/23096711
http://dx.doi.org/10.1038/jid.2012.370

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