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Acute administration of ketamine in rats increases hippocampal BDNF and mTOR levels during forced swimming test

INTRODUCTION: Previous studies have shown that a single sub-anesthetic dose of ketamine exerts fast-acting antidepressant effects in patients and in animal models of depression. However, the underlying mechanisms are not totally understood. This study aims to investigate the effects of acute adminis...

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Detalles Bibliográficos
Autores principales: Yang, Chun, Hu, Yi-Min, Zhou, Zhi-Qiang, Zhang, Guang-Fen, Yang, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572668/
https://www.ncbi.nlm.nih.gov/pubmed/22970723
http://dx.doi.org/10.3109/03009734.2012.724118